Stomatitis- any experience?

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Re: Stomatitis- any experience?

Postby connie » Thu Aug 04, 2016 4:21 am

I'm just seeing this -- so sorry, Amanda! How very scary!

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Amanda
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Re: Stomatitis- any experience?

Postby Amanda » Thu Aug 04, 2016 6:57 pm

Our recheck was yesterday. He has lost 10 lbs since this started and the vet is very concerned by the dramatic muscle wasting. We cut steroids yesterday and will drop again Monday and be done with them Friday. New antibiotics for new massive sores in his mouth. Adding a daily antibacterial mouth rinse to help stop those or at least reduce severity. May try new steroids next week depending on how things are going. Sad to see him struggle like this.

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Re: Stomatitis- any experience?

Postby SherriA » Thu Aug 04, 2016 7:19 pm

Oh Amanda, that must be so disheartening. Sending good thoughts for Landis, and for you too.
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Amanda
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Re: Stomatitis- any experience?

Postby Amanda » Thu Aug 04, 2016 9:11 pm

Nose bleeds just started again. Really feeling worried. Started a Chinese herb that I had on hand from the last round of nose bleeds. I hope it helps.

Financially, we can't keep chasing a firm diagnosis. I hate to see him like this but it isn't time to let him go yet either. Pray for him to heal somehow and soon. Probably going to switch to another immunosuppressive therapy asap.

A friend of mine had rehomed one of her service dogs years ago and just found out she passed away. Ate breakfast like usual. Family went out to run errands. Came home to the dog cuddled up with her toys, gone in her sleep. 12 years old. I wish it were that peaceful and easy for all dogs.

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Re: Stomatitis- any experience?

Postby MaisyPancakes » Fri Aug 05, 2016 12:32 pm

Oh, Amanda. :( I hope TCM helps with the nose bleeds. Is it Yunnan Baiyao? It seemed at first that the steroids were helping with the symptoms—how frustrating. :( I'm sorry that you're having to put out fires as you go. Sending all healing everything your way. xoxo

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Amanda
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Re: Stomatitis- any experience?

Postby Amanda » Fri Aug 05, 2016 1:53 pm

Yes. Yunnan baiyao. Vet called today and we talked extensively of the options. He is leaning toward bullous pemphigoid. It is rare and diagnosis of lesions is difficult because they blister and pop quickly. You have to catch the fluid in the blisters before they burst. He asked me to look it up and two medications that he recommends and see what I think. He has one of them in stock that he will give me for free. Another client paid for them and then had to put their dog down and gave it back to the hospital so he has it if I want it. It's a chemo-type immunosuppressant.

He is also very concerned about his body wasting away. Landis was only on the high dose of steroid for 10 days. This level of wasting shouldn't happen for 3+ weeks at a high dose. So we are wondering if this symptom is separate from the drugs and more related to the disease.

My first readings of all of this show prognosis on this is guarded to poor. Death is related to poor tolerance of treatment. Bracing myself, but he may be leaving us sooner than we had hoped.

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Re: Stomatitis- any experience?

Postby Amanda » Fri Aug 05, 2016 8:18 pm

Decided to start azathioprine today. Blood draw and recheck next week to make sure it isn't killing his kidneys or destroying his bone marrow. Crossing fingers and hoping for the best.

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Re: Stomatitis- any experience?

Postby Calypso » Sat Aug 06, 2016 7:42 pm

Oh my goodness! What a horrible roller coaster. I'm sorry. I hope the treatment is effective for your boy.

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Re: Stomatitis- any experience?

Postby UpwardDog » Sun Aug 07, 2016 8:31 pm

Oh my goodness, I am so sorry and sad to see these new developments. Poor Landis and poor you.

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Amanda
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Re: Stomatitis- any experience?

Postby Amanda » Sun Aug 07, 2016 10:41 pm

Azathioprine on board since Friday. He is looking healthier to me. Nose bleeds have stopped. Mouth lesions are healing. We do a blood draw Thursday or Friday to see if his kidneys and bone marrow are tolerating it ok. And that's it. Watch and wait. He seems to be putting a little weight back on. So that is good and he isn't panting and pacing around like he was for a little while. So I am hoping for good things.

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Re: Stomatitis- any experience?

Postby MaisyPancakes » Mon Aug 08, 2016 9:05 am

So glad to hear this good news! Keep it up, Landis! Hugs your way, Amanda.

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Re: Stomatitis- any experience?

Postby UpwardDog » Mon Aug 08, 2016 5:34 pm

Yay, I'm so glad there is some improvement. Cook him a big steak supper from me.

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Re: Stomatitis- any experience?

Postby JudyL » Fri Aug 12, 2016 9:45 am

I'm sending you all the best wishes I can. Hopefully you are still seeing improvement and the labs will not show any adverse effects from the new drug.

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Re: Stomatitis- any experience?

Postby connie » Sun Aug 14, 2016 5:34 am

All paws and fingers crossed here that this protocol is effective.

On a side note, I lost my first Sheltie to something similar: dermatomyositis, also called bullous ulcerative dermatitis with basal cell necrosis. She tolerated Pred reasonably well for a couple of years, but it didn't keep the disease contained and the DM affected her organs. DM is an autoimmune disorder in Shelties that is heritable and often manifests in mid-life, as Briar Rose's did; vaccines can be the trigger, as they apparently were with her. I didn't know any better back then and she was vaxed annually.

Not saying this to be a debbie downer, sorry it reads like that. :(

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Re: Stomatitis- any experience?

Postby MaisyPancakes » Fri Aug 19, 2016 7:31 am

How's Landis, Amanda? Sending hugs and positive everything! :)

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Amanda
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Re: Stomatitis- any experience?

Postby Amanda » Sat Aug 20, 2016 12:17 am

Seems ok. I decided to wait on the blood test for another week. I just really want to give the meds time to work fully. He still has small lesions in the back of his mouth but they are healing. Some things I have read said blood tests at 2-3 weeks so I wanted to give it a little more time. He is putting weight back on so that's good. And he seems happy. Thank you for asking!

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Re: Stomatitis- any experience?

Postby SherriA » Sat Aug 20, 2016 7:58 am

I'm so glad to hear he's feeling better!
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Re: Stomatitis- any experience?

Postby MaisyPancakes » Sat Aug 20, 2016 9:36 am

That's good news, Amanda! Happy Landis. :) Thanks for the update!

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Re: Stomatitis- any experience?

Postby LisaT_II » Sat Sep 03, 2016 5:55 pm

Bartonella comes to mind. Incredibly hard to test for because there are all different kinds, though there may be a dominant form in cats? Steroids would not be indicated if this is infection.
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Re: Stomatitis- any experience?

Postby LisaT_II » Sat Sep 03, 2016 5:56 pm

Oh, btw, that can be passed on to others in the household, including humans :(
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