I hear you about the common-but-kind-of-scary-once-you-look-into-it-ness of Pepcid and the like. I think it's much more preferable than the PPIs, though, and easier to wean off of. My vet and I tried tons of things to ease her off of Pepcid, and I made a spice mix with cardamom, anise, fennel, cinnamon, ginger, black pepper, cayenne, cumin, orange peel, rosehips — and put a bit in a capsule and gave it with food. I can't go look in my MP journal now to recall what each of these were supposed to do, but I do know that the purpose was to restore GI comfort and and maybe reduce/inhibit histamine? I also dried minced fresh ginger and added that to the capsules sometimes. I had to wait on the ginger because it can sometimes be too irritating. The go-tos like Insanely thick barley water and slippery elm and marshmallow type things also helped, too. I was scared and desperate at the time (she lost a ton of weight and I just needed her to absorb nutrients), so tried all the above at once...so I can't quite pinpoint what worked, but eventually, she was much better. Maybe this syndrome is a whole different thing, but for general GI distress, these are the things that helped us.