Apoquel

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etexlady
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Apoquel

Postby etexlady » Mon Jul 27, 2015 1:47 pm

My little toy poodle, Trinnie, has terrible allergies. Her vet thinks it is most likely seasonal allergies rather than food related. She's had a couple of "allergy shots" (Convenia) for her skin inflammation and two rounds of Prednisone. She gets relief during the two weeks she takes the Prednisone but as the dosage is tapered down, the itching increases. The vet said she's had enough Prednisone so today he prescribed a fairly new drug called Apoquel to try for 2-3 weeks. It's not a steroid so she could be on it long-term if necessary but we are hopeful the allergies are truly seasonal and will go away in a couple of months. The stuff is expensive - 35 tablets were $73! Has anyone else had this prescribed for their dogs and, if so, did it work?

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Re: Apoquel

Postby whiteboxerboy » Mon Jul 27, 2015 1:58 pm

A Boxer I know has been taking it for a few months now with great results - no more allergy symptoms at all.

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LisaT_II
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Re: Apoquel

Postby LisaT_II » Mon Jul 27, 2015 4:23 pm

Some misc info in here, and at the end of the thread an update from a user: http://germanshepherdhome.net/forum/ubb ... s/309154/1
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Re: Apoquel

Postby Sabine » Mon Jul 27, 2015 5:21 pm

Be very, very careful if you are considering it for long term use. I know many vets push Apoquel as a "miracle drug with no side effects", but that's actually far from the truth. It's an immunosuppressant

This is a nice run down of need to know information:
http://www.2ndchance.info/Apoquel.htm
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LisaT_II
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Re: Apoquel

Postby LisaT_II » Mon Jul 27, 2015 5:49 pm

Great article Sabine, I added it to the GSD thread too.
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keeksuka
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Re: Apoquel

Postby keeksuka » Tue Jul 28, 2015 11:03 am

My alleric-to-EVERYTHING dog has been on Apoquel for about a year and a half. She is 11 and has so far had no negative effects that I have noticed or that bloodwork has shown, and it really has been a "miracle" drug for us. That said, I realize there are risks and worry about them, but we had nothing left to try. If your dog is suffering and it's for short-term use, I'd go for it. If it's a long-term problem and your dog is miserable, exhaust all your options before moving to Pred, Atopica, or Apoquel - IMHO.

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Re: Apoquel

Postby etexlady » Mon Dec 12, 2016 8:00 am

Original poster here. My dog has been taking Apoquel for about 15 months. In addition to the Apoquel, she takes benedryl twice daily. It was great initially but as time went on she began experiencing more itching, licking, hot spots, staph infections, etc. The most recent problem is ear infections. I've probably spent over $500 in the past two months getting her ears packed with medication (both ears twice and one ear three times), antibiotics, etc. One ear has been especially difficult to clear up and today the vet suggested we get a culture and sensitivity done to know what we are dealing with. Once we get her past this problem, I plan to talk with the vet about Apoquel. I think her immune system is so depressed by the Apoquel that we will be dealing with episodes like this over and over and over. My worry is that there is nothing left to try and we'll go back to her being miserable and scratching and itching all the time.

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SherriA
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Re: Apoquel

Postby SherriA » Mon Dec 12, 2016 12:42 pm

One of the dogs in my senior program had a similar experience. Apoquel worked well for awhile, but it's effectiveness gradually lessened over time, and she too was getting severe ear infections in addition to the itching. Her adopters took her to a dermatologist, and I'm not sure what the final course of action was (some kind of shot, I believe) but her allergies have improved significantly. If you want, I can try to find out what the dermatologist is doing. If you have access to a specialist like that, I'd see if you can get her an appointment. It's expensive but if it saves all those other vet trips, then it pays for itself over time.
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Re: Apoquel

Postby maxs_mommy » Mon Dec 12, 2016 9:23 pm

My (Max's) ophthalmologist talked to me about it since she frequently works with the local allergist and said that for environmental allergies it works fairly well, not so much for food allergies. So the question of efficacy also depends on knowing what allergies you're dealing with. Since none of this occurs in a vacuum, you may need to re-evaluate foods, environment and other potential allergens. For Max, the itchies were largely caused by foods. Knowing that, and thanks to our local independent pet store who armed us with samples, we were able to find a food to feed and know what foods to avoid which trigger the itchies. Also, do you know why the ears are infected? Yeast? Bacteria? Are you on a good probiotic? Our experience was that the itchies led to the sores which got infected and the circle just kept spinning out of control. Clean up the sores to stop the spiral then find the source of the itching. If all your vet is doing (not saying they are), is addressing the surface symptoms but not the underlying cause then you're in for a never ending cycle of suck.
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SherriA
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Re: Apoquel

Postby SherriA » Tue Dec 13, 2016 8:23 am

Oh, yes, clean up the sores! That was another thing the dermatologist really focused on. He got all those sore, red, infected spots treated so they weren't being spread around poor Babe's body.
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etexlady
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Re: Apoquel

Postby etexlady » Thu Jan 12, 2017 8:37 am

Sorry to be slow to respond but had to get through the holidays and regroup. Thanks to everyone for the replies. The vet did do a culture and sensitivity and, not surprisingly, the ear infection was caused by staph intermedius. It was a strain of staph that was resistant to most of the commonly prescribed antibiotics. We decided to use a liquid form of silver sulfadiazine. I have to flush the ear and then inject the silver sulfadiazine into the ear twice daily. At the two week check things were much improved. We go for another two week check tomorrow but I have been warned that the treatment may take up to two months to be totally effective. The vet was telling me about a new injection for allergies called CADI (Canine Atopic Dermatitis Immunotheraputic). It's use is restricted to vet dermatologists currently although my vet said they could order it if I wanted to try it.

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LisaT_II
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Re: Apoquel

Postby LisaT_II » Fri Jan 13, 2017 2:21 pm

Not sure if you might find some info in these threads, I have no experience with the medication, though we do have extensive allergies here.
https://gidgetsjourney.wordpress.com/
http://germanshepherdhome.net/forum/ubb ... s/309154/1
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