Cancer clinical trial

Discuss topics ranging from general care to diet, vaccinations etc.
connie
Built-in Forum Feature
Posts: 11192
Joined: Mon Feb 06, 2006 12:53 pm
Location: Chicago
Contact:

Re: Cancer clinical trial

Postby connie » Fri Aug 10, 2018 12:03 pm

Still rooting for Max, what's the procedure for his further treatments?

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Sat Aug 11, 2018 11:37 pm

His white cells are back up so we're on a week of Doxy. Apparently this is not abnormal but we won't be doing another treatment this month based on the bloodwork and life's schedule. He yelps in pain like something's poking him in the mouth once in a while and it's clearly uncomforatable but of course he won't allow anyone to look into his mouth without sedation. Sigh. I have a appointment on Monday for a nail trim and I"m going to have a convo with his regular vet about this.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

connie
Built-in Forum Feature
Posts: 11192
Joined: Mon Feb 06, 2006 12:53 pm
Location: Chicago
Contact:

Re: Cancer clinical trial

Postby connie » Mon Aug 13, 2018 7:04 am

Paws and fingers here are all crossed for you and Max, it's got to be like walking on a high-wire.

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Mon Aug 13, 2018 7:06 am

I hope your vet has some ideas. Poor Max and poor you. This is such a balancing act.
Image

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Wed Aug 22, 2018 11:41 am

So the next treatment was supposed to be on Friday but I nixed that idea because we're going on vaca on Sunday and I didn't want to have side effects for the inlaws and pet sitter to manage. Last time the side effects manifested for about a week after and now he's stable. Now the next treatment is the 7th of Sept. As much as I hate waiting, I'd rather be the one to manage any weirdnesses.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

connie
Built-in Forum Feature
Posts: 11192
Joined: Mon Feb 06, 2006 12:53 pm
Location: Chicago
Contact:

Re: Cancer clinical trial

Postby connie » Thu Aug 23, 2018 5:30 am

Sounds like the side effects are a consideration in planning the treatment -- that's too bad, but probably to be expected. What are the objectives of the clinical trial?

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Thu Aug 23, 2018 5:59 am

That sounds like a sound plan. I'm keeping my fingers crossed that the side effects are manageable and this treatment helps sweet Max
Image

User avatar
MaisyPancakes
Permanent Resident
Posts: 8528
Joined: Fri Feb 17, 2006 11:02 am
Location: Minneapolis, MN
Contact:

Re: Cancer clinical trial

Postby MaisyPancakes » Fri Aug 24, 2018 7:25 am

Good plan! :) Sending no-mo-side-effects vibes to the softest curly curl boy!

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Fri Aug 24, 2018 9:46 am

Connie, the study goals are to kill, or at least substantially reduce, the mouth tumor and reduce the mets. I took him in for a nail trim and my vet got a glimpse of the tumor this morning. She thinks it's gotten flatter and smaller but we'll see for certain when he goes on the 7th and can get a good look at it under gas. The main tumor was growing toward the back of the mouth toward the throat so that's why the intubation and gas. He is gaining weight, up 1.5# in a month which is huge, he needed to gain because he had nothing to lose and was. Ideally he'd be between 23-25 lbs so we're in range with the weight gain. Nausea was the known side effect for this which we had some of but because the tumor is in the mouth there was some sensitivity and pain which we've got a handle on but I'm not going to ask someone else to manage any weirdness.
Sorry this is rambling. I'm exhausted from getting my butt kicked with work last night.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
MaisyPancakes
Permanent Resident
Posts: 8528
Joined: Fri Feb 17, 2006 11:02 am
Location: Minneapolis, MN
Contact:

Re: Cancer clinical trial

Postby MaisyPancakes » Fri Aug 24, 2018 9:59 am

YAY for weight gain and shrinkage/flattage!!! That's huge! <3 :thumbup: :laugh: Hope you get some rest!

User avatar
JudyL
No, I don't have a life!
Posts: 5924
Joined: Mon Dec 17, 2007 9:53 pm
Location: Delaware

Re: Cancer clinical trial

Postby JudyL » Sat Aug 25, 2018 11:33 am

I'm glad you are seeing some positive results out of this despite the side effects! At least you have ways to minimize those, and I completely understand your decision to not place that burden on those caring for him in your absence.

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Tue Oct 02, 2018 10:41 am

Today was the 3rd treatment and, after two weeks of normal range white cells, the tumor has shrunk 1 cm in both directions. Hooray! They said it's not uncommon for the tumor to become infected at some point during treatment but I'm hoping we won that rodeo already with the first round. I'll pick him up shortly and let him sleep off the anesthesia.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
MaisyPancakes
Permanent Resident
Posts: 8528
Joined: Fri Feb 17, 2006 11:02 am
Location: Minneapolis, MN
Contact:

Re: Cancer clinical trial

Postby MaisyPancakes » Tue Oct 02, 2018 10:46 am

Yessss!! That is a ton of shinkage!! Go shrinkasaurus Max! :D Hope he has some awesome dreams sleeping off the zonks. :)

User avatar
JudyL
No, I don't have a life!
Posts: 5924
Joined: Mon Dec 17, 2007 9:53 pm
Location: Delaware

Re: Cancer clinical trial

Postby JudyL » Wed Oct 03, 2018 8:35 am

Wonderful news! I hope you continue to see more shrinking. How many sessions are left?

User avatar
Jen
Built-in Forum Feature
Posts: 14310
Joined: Sat Aug 06, 2005 8:34 pm
Location: Portland-ish, OR

Re: Cancer clinical trial

Postby Jen » Wed Oct 03, 2018 6:56 pm

Wow, that's awesome!!!

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Wed Oct 03, 2018 11:50 pm

I was told there's not a definitive number of treatments, we'll go until it doesn't work or the tumor is gone. He was so zonked from the anesthesia yesterday that he was snoring as I carried him to the car. Something about the treatment also seems to cause diarrhea because he had 4 bouts of poopsplosion last night. He seems to have rebounded today with alertness and the gut aliens have mostly moved on, thanks dog. Blood draw on Tuesday for white cell count and maybe another treatment toward the end of the month.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

connie
Built-in Forum Feature
Posts: 11192
Joined: Mon Feb 06, 2006 12:53 pm
Location: Chicago
Contact:

Re: Cancer clinical trial

Postby connie » Sun Oct 07, 2018 4:40 pm

Wow, how great that he's gotten that result so far! Sorry about the poop situation, I guess you have to take the bad with the good. :sick:

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Mon Oct 08, 2018 5:27 am

Those are amazing results!
Image

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Fri Oct 12, 2018 1:35 am

In this week's edition of "weird bloodwork" we have slight anemia and higher ALT & ALP. ALT is always out of range because of the Cushing's but it's higher still, apparently. Hepatic support and B complex vitamins on board. Recheck on Tuesday.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
emmas_mom
No, I don't have a life!
Posts: 4390
Joined: Fri Aug 26, 2005 9:25 pm
Location: BC Canada
Contact:

Re: Cancer clinical trial

Postby emmas_mom » Sat Oct 13, 2018 7:39 am

Glad to read the tumor is shrinking. I hope the side effects diminish quickly.
Mom to Maggie, Emma and Allie, and occasional foster mom. Ever remembering Sadie, Charley, Caleb, Belle, Oliver, Shiloh, Eddie and Mitzi.
My blog: http://www.mylifewiththecritters.blogspot.com

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Mon Oct 15, 2018 9:19 am

fingers crossed for better liver numbers tomorrow!

Oliver had ALP through the roof the entire time I had him. I tested for everything under the sun and we never found what was causing it but it also never seemed to affect him. Hopefully this is a blip, but if it isn't my fingers are crossed that Max will not be bothered by it.
Image

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Tue Oct 16, 2018 11:17 pm

The trial vet was nice enough to send all the labs to my vet for a comparison arc/graph. Max is doing well on his supplements and did a blood recheck today.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
MaisyPancakes
Permanent Resident
Posts: 8528
Joined: Fri Feb 17, 2006 11:02 am
Location: Minneapolis, MN
Contact:

Re: Cancer clinical trial

Postby MaisyPancakes » Wed Oct 17, 2018 8:32 am

Yaaay, I'm so glad that this trial has been yielding super great results for the Max!!

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Thu Oct 18, 2018 5:05 am

Excellent news!
Image

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Fri Oct 19, 2018 12:01 am

And now something else is weird. I expected to have another treatment Tuesday but it looks like we're going in for more blood work instead. I just got a call from the receptionist today to schedule. I'm going to follow up with the vet on Friday.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
MaisyPancakes
Permanent Resident
Posts: 8528
Joined: Fri Feb 17, 2006 11:02 am
Location: Minneapolis, MN
Contact:

Re: Cancer clinical trial

Postby MaisyPancakes » Fri Oct 19, 2018 9:45 am

Sending "just too much Maxness in the blood and nothing bad-weird" vibes! You'll do the bloodwork on Tues?

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Fri Oct 19, 2018 9:53 pm

We do more bloodwork Tuesday. I got a call today, his RBC's are back to WNL, the ALP is coming down but still high.
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Tue Oct 23, 2018 7:27 am

coming down is good, though!
Image

User avatar
maxs_mommy
Yes, I do have a life!
Posts: 2512
Joined: Wed Jan 05, 2011 10:29 pm
Location: Missouri, USA
Contact:

Re: Cancer clinical trial

Postby maxs_mommy » Mon Oct 29, 2018 8:14 pm

Another treatment today, another 1 cm of shrink radially across the tumor and some shrinking of depth of the tumor so we forge on. No infections of the tumor and if we can only get the liver levels down we'll be good. Boy wonder is snoozing like the dead but did much better with the anesthesia. He was ambulatory when I picked him up which is an improvement over last time, ;) .
Max "the ninja"-American Cocker Spaniel G-day 3/2009
Charlie "the middle child"- Orange Tabby G-day 7/2005
Sadie - Grey Tabby 9/1996-8/4/2012 RIP

User avatar
SherriA
Built-in Forum Feature
Posts: 14054
Joined: Sat Feb 03, 2007 8:52 am
Location: Bethel, CT

Re: Cancer clinical trial

Postby SherriA » Fri Nov 02, 2018 3:53 pm

I missed this when you posted it, but hooray for continued shrinkage! I'm glad that the anesthesia was easier on him this time. Fingers crossed for those liver levels.
Image


Return to “Care, Health & Nutrition”

Who is online

Users browsing this forum: No registered users and 17 guests